Which tests should the nurse monitor in a patient who takes somatropin

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    • When not in use, the Nutropin AQ NuSpin should be refrigerated at 36° to 46°F (2° to 8°C) to maintain the potency of the medication. The NuSpin device should never be frozen. During use, it is recommended that patients have their device outside of the refrigerator for no longer than one hour per day. If the Nutropin AQ NuSpin is kept outside of the refrigerator for longer than one hour, the medication should not be used. Direct patients to call 1-866-NUTROPIN for additional assistance. Patients should keep their medication out of direct sunlight.

      When traveling, instruct patients to keep their device dry and stored within the appropriate temperature range noted above.

      If the Nutropin AQ NuSpin requires cleaning, a damp cloth should be used.

      Patients should never place their injection device under water. If their device is accidentally immersed, they should remove it from the water and dry it immediately. Also, remind patients to never use alcohol when cleaning their device.

      Patients are instructed to call 1-866-NUTROPIN, their specialty pharmacy, or their healthcare team if the Nutropin AQ NuSpin malfunctions.

      Read Important Safety Information

      Patients must use a new needle for every injection. The needle is sterile only for a single injection. The following needles fit and work on the NuSpin:

      Needle Disposal

      The NuSpin device is prefilled and the cartridge cannot be replaced. When the NuSpin device is empty, it should be disposed of, with the needle attached, by using the same procedure for needle disposal.

      Patients should be instructed to always store disposal containers out of the reach of children. Patients/caregivers should dispose of needles in a proper sharps disposal container. Improper disposal of needles and other medical sharps can cause needle-stick injuries.

      Advise patients to throw away used needles safely; they should check with their local health departments for guidelines. More information is available here: Genentech Information on Sharps Disposal.

      If the specialty pharmacy does not provide a sharps container, patients may call the Nurse Hotline 1-866-688-7674 to have one delivered.

      The Coalition for Safe Community Needle Disposal - A searchable database of locations accepting used sharps

      Specific Important Safety Information

      Patients should be sure to inject Nutropin AQ® at a different recommended place on their body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection.

      Patients should not inject Nutropin AQ until they have been properly trained. If patients have not been trained yet, they may call 1-866-NUTROPIN (1-866-688-7674) to set up an appointment.

      Read Important Safety Information

      • Nutropin AQ must be refrigerated at 36° to 46°F (2° to 8°C), and cannot continue to be used beyond 28 days after initial use and should be discarded. Nutropin AQ should not be frozen.
      • The Nutropin AQ cartridges are light-sensitive and should be protected from light when not in use.

      Please see Nutropin Full Prescribing Information for additional Important Safety Information.

      Nutropin AQ is available in the United States by prescription only.

      For questions, patients may call 1-866-NUTROPIN (1-866-688-7674) or visit Nutropin.com.

      Your next step is to find out as much as you can about your condition, and how Nutropin AQ® therapy may help for appropriate patients. To get you started, we’ve put together a Patient Education Kit. You’ll get your kit when you are prescribed Nutropin therapy. Inside the kit, you’ll find everything you need to understand and get started on treatment, including:

      NuSpin® User Guide (English/Spanish) - Download PDF (1.4 MB)

      Nutropin AQ Monthly Therapy Tracker - Download PDF (2.2 MB)

      Nutropin GPS™ Co-pay Brochure - Download PDF (2.7 MB)

      If you have questions, talk to your healthcare providers’ office or call us at: 1-866-688-7674.

      Enroll in the Co-pay Card Program online.

      Change of Insurance Mailer - Download PDF (1.3 MB)

      • Clear zip bag for medication storage

      To request a full Patient Education Kit or to ask any questions, call us at 1-866-NUTROPIN (1-866-688-7674).

      Headache, nausea, vomiting, fatigue, muscle pain, or weakness may occur. If these symptoms continue or become bothersome, inform your doctor or pharmacist promptly.

      Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

      Tell your doctor right away if you have any serious side effects, including: development of a limp, persistent fatigue, unusual/unexplained weight gain, persistent cold intolerance, persistent slow heartbeat, fast heartbeat, ear pain/itching, hearing problems, joint/hip/knee pain, numbness/tingling, unusual increase in thirst or urination, swelling hands/ankles/feet, change in the appearance or size of any mole, persistent nausea/vomiting, severe stomach/abdominal pain.

      Get medical help right away if you have any very serious side effects, including: vision problems/changes, seizure, severe headache.

      Rare (possibly fatal) lung/breathing problems may be caused by this medication in children with Prader-Willi syndrome. Those at higher risk include males, severely overweight children, or those with serious lung/breathing problems ( such as sleep apnea, lung infections, lung disease). Children should be checked for certain breathing problems (upper airway obstruction) before and during treatment. Heavy snoring or irregular breathing during sleep (sleep apnea) are signs of airway obstruction. Tell the doctor right away if these signs occur. Also report any signs of lung infection, such as fever, persistent cough, or trouble breathing.

      Somatropin may increase your risk of getting a tumor or cancer. Discuss the details and the risks and benefits of this medication with your doctor.

      A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/severe swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

      This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

      In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

      In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

      Page 2

      Headache, nausea, vomiting, fatigue, muscle pain, or weakness may occur. If these symptoms continue or become bothersome, inform your doctor or pharmacist promptly.

      Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

      Tell your doctor right away if you have any serious side effects, including: development of a limp, persistent fatigue, unusual/unexplained weight gain, persistent cold intolerance, persistent slow heartbeat, fast heartbeat, ear pain/itching, hearing problems, joint/hip/knee pain, numbness/tingling, unusual increase in thirst or urination, swelling hands/ankles/feet, change in the appearance or size of any mole, persistent nausea/vomiting, severe stomach/abdominal pain.

      Get medical help right away if you have any very serious side effects, including: vision problems/changes, seizure, severe headache.

      Rare (possibly fatal) lung/breathing problems may be caused by this medication in children with Prader-Willi syndrome. Those at higher risk include males, severely overweight children, or those with serious lung/breathing problems ( such as sleep apnea, lung infections, lung disease). Children should be checked for certain breathing problems (upper airway obstruction) before and during treatment. Heavy snoring or irregular breathing during sleep (sleep apnea) are signs of airway obstruction. Tell the doctor right away if these signs occur. Also report any signs of lung infection, such as fever, persistent cough, or trouble breathing.

      Somatropin may increase your risk of getting a tumor or cancer. Discuss the details and the risks and benefits of this medication with your doctor.

      A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/severe swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

      This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

      In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

      In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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